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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '453c8003ccd616115dc00b3c87888c27361e1c1c73c9a3b8ea9f0485ea1abb36' 
  AND token = 'I72XdK4kWFPqooRHxQgfwbH756vNFme4mIaO/+dHQDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}