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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781f08995ee0c7964f7ee9c7108be447650affb52e031eecdc4ce211e40df8aa' 
  AND token = 'eTQTJ9eLEjgWUQm/I1cLy/vv6Wy3xbb8Jw3fj6SdNYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}