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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fd33cf65de1fd3bd7e290c585708851135ed7a5d1a62f38cc40a0eac2b2af21' 
  AND token = 'IIUQCcLYWofhKCsWHtKD14B/b8BeREuO33BI7Cifu5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}