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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2565ce1492523c0f3fee9a093d2a8dea1e596f535ec1b49955e39cd224927ec4' 
  AND token = 'rPO9dEwAl3HEyoOr2xAIb6HkFw3YEO5nIbLs16lMu74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}