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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf3ab7c7d066e9f353f1b7931c79cb1a453ec9a19253c92638ac7afa43021545' 
  AND token = '+4pgwPckmZbxBmXwh9Dy49f3bXc2ZH/+/ngT856+mss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}