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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1253ce08e606388372eb869740d3f6616eff0adb2fe6f381ed766be9be50a92' 
  AND token = 'u3kihvR1jrKe09It9Bfs7LCPQhr1HH3d/BTicLfya9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}