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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db865356d8cbc5219edf78c7cf3f6d44b9a4c697879d5be7f22518290fc5eb61' 
  AND token = 'oFdXxDW6H2q2/yWsENw7jOrzpTd8rb4WP+dU2WkPT+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}