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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db072ce9626da832b39c1a1a9eeedd1f307cae75d453c94a7b777602671b5e45' 
  AND token = 'x7Zf+12Pgrnjxceyd/s2MSEdjVpEDwq8CNq52dBTsZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}