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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e19dd0c207428f953bb39ec6fe4a592301440e7aabf15f3888e06bb41c3e9067' 
  AND token = 'eK3F5wtOa7No/LR37VqV81sZVg493qKG+6e7W9wleUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}