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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd23450fe5eb360aee2007bc78beccfc7782fcbe4dac8a21b8452d2876eeee41a' 
  AND token = 'vceiUETD7r7dGzvwgndgUzNLre3JjXGHGSibcjhsy8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}