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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e841c86be4e84c925a4e6318ac0532aa6ef956956d11623a122baa4ae57e1646' 
  AND token = 'Y8dD3c+N2GazySMbP8XUtjPfu3SiHrQF4PDqOyVA7z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}