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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e44c3ed5df01b0ad37e4e7f1c2ea121839c584314294df452b278ccc8ece8e09' 
  AND token = 'f32gIYT6QM/Dwbb+NhohoSSyVNgete+XjpFdj0wFjKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}