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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b665b3efe43655b3f793728e09d1c5886b87ca952ba0f2201178a91fa85bf9a5' 
  AND token = 'XL/Hf/g+VDUVrO2c1ImERFTAY/5mmWY98Lt1SIansY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}