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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ab6df011125f6a8455f091ab3880bd0489da5b59a50a6965ec40c929488bc0e' 
  AND token = 'GGv557xxL5u/3wwexaTLHDX2jPHTYO728siTMJ7Fp4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}