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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f32a283509f1986bf769d0b0b85bd880eb2264088001267b54d6535f978c76c3' 
  AND token = 'XZ4yzBXIE6o0CUgT+ygBz2cIBNdMxSxZM4gx1g6Pg7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}