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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8214fd5e4b0b79ade3d9faf93245eab965d3dc00812f17b44e6c0ae5d30fd163' 
  AND token = 'ID7kk3MhBoOFYn6B5qVxOqPOp85xK64JSJSLMnL4Waw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}