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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bed9daae4a49b15d6b28d5786c8974bc9343782a7887780b4440ae165b8f422' 
  AND token = '6uz3a1sS5HHAV/zft7Hmhv/9KcbefFBr6gA0ZB+gFG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}