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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f8a85cac0c84eb59b212030dfac72b432a0c0e9c94788ca3f9ffa13c0a8cb79' 
  AND token = 'EBUGFx6JaPfTdJfh0RPy7C2gFdUKnJZWnVvoTdUewhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}