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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '728142bdd27259639e5db7431b966dc8fd4dc51a2ac9ac035c15d2dec2cb3ca1' 
  AND token = 't8WPvNxdHPztSgW/LvAm7fL+xl7+czeD1WtGfSfm6l4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}