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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9786e009d603a987163a00204553173c212f04c01d86e04e4ff36f2c201e03c9' 
  AND token = '2lHpxVBT4+FitTUxTR1uDBWl4Py8TOPSCgeKY7YNlo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}