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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9de580212063cc4606b2b09fdb4f2a55baf5f7445e8d5d0f8f2fc7b69c179bc4' 
  AND token = 'cfZLyTyCXPbMAKEOS2+j0TZGAyh12GlL6qOxlkDzjvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.05487

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}