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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd6b843629cd25e871e6d75d49122add4fc42fb3003b0576b22428cc2858d7a4' 
  AND token = 'dbmeHGLdH4JL39sQz+l9M2hTuC49o4X/pma6jmr7FcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}