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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5be4e582aa0fb56d6d8055ec33ce54166659eb387faf538dfd577c2ca2d86d57' 
  AND token = 'tlUjzlDYKe0R6fj98vyEWDn3uDDDKcS4AFAUdfqy7tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}