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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf9fcad77abb0ba5079d57c5c6fddd7460dc9f2412ebade4f0fd7558275323c2' 
  AND token = 's9HqyvA7cS/joxslUyH7RZv8N7UH187QqalUmei3IMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}