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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2da38ca9405c645e66fc3a5ce50cfab99939c057d961fea4c4340a2918cf7abe' 
  AND token = 't3pIYqmLsTlWjCit3Gbjc/3+p+6fv5HVjMS2eLENZ64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}