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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246cb886628b9690561afd96b76177c34ec2d22e2c44c1cc1019a5229414e178' 
  AND token = 'BRZnfPswmwQQ0BI0jgmiaxeT0FZf63jovk3CakN5cbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}