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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '174605bba56be5a31ec0684c02b2667ea268f5a63c3ae06a8a11b5d01f063277' 
  AND token = 'TxTfG79Uya1JhBIdO23Z0GyqaKQgSymVo/KwLe9vVIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}