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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20ed1ef839bfed2d27bf356a63f641f1b3b48ceb90f87344e06b1d28a5be76d8' 
  AND token = 'zuKvx+Q+rQca+5hBD9e9t0PUvaLnRmiu8BCVyz4e3uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}