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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6de2ff028fb6ba893932e9e28266e3427e207214daf77d6e79dec2d743226fc3' 
  AND token = 'sgoGpmztHVidwu032uDB6mikKv8tcfsduMAjdbBzix0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}