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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b928dde6318bbf1e7583ad4151f2d37a815cd2765e6891dcb2b9ef977b649c56' 
  AND token = '+8oxYf1FVWeNyyAeTZyZEgK4f1ZAnhDg8VzXdJx45Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}