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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5c9b9598fbdd5c9b7cbafd7504fb7e93441a9c0f41cb78d232707125cecf670' 
  AND token = 'Ac6Tz0Q2pHYoVeaCsvzeQEQH/D2RogTYktPidAN/I28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}