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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a894ef4dc1a9b48e746413420d973136ce3c2a69cb232f37862ebb278950b3e3' 
  AND token = 'k+9plbwGBxJ8bHRPdo/tubJGr70byZlpVTyA+KmyKmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}