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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9977cf9cb11e6f467b443391905b285bdbd87dd74287ef38e8f3ffcc82c3f6e3' 
  AND token = '2QNd5qciijlR+hrbc82ceS5LiZQiXnkoPt1qKrUp3Vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}