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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8642ef0ed0fbdc274d7f06d26bebfa3b98109d91d5082f7ef210c5e11ea00e39' 
  AND token = 'ndTI56i/xki8915JNOmzkpKOQDWLWhwHB0lWM9CJUUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}