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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0abdd34a7fded12abd175e5f35e87e8ac5ce67c8e8897f7e9dd1b6bc61282e91' 
  AND token = 'AIHYVrneT9wIT3Zgp6Sc2s514viwgUwQ/Wfb7nv796M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}