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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a467f185c0664a4b0797a84006eab5c36fbf646022c160fc9653c1f5a50dfe7f' 
  AND token = 'djsTbVoRPsN4Fc7/3EPr6a8aNCqzkl4jK/CMD0wQL6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}