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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7d3ea45729849f254ed93bb8d2446bc45c8d23f20ba458a38c97a0387c8d61d' 
  AND token = 'y+2vHd8PV7VsZssMjI5MzZvKC2yC8/Rg9WQtuAfHbUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}