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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f01e8ab330fd6ffea8f88e71e6d53862a228f6c1dab21a8bf48d883518d4c60' 
  AND token = 'u4K1Bhdh6ZfbfQgJKGNN8dGpujENiLECk3315Squvw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}