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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f188aa7aef8752ce8e0848b571f305bd38f2bed2f59be10d4722712661700c' 
  AND token = 'vJCY72dXF8VnCKnR6ui7tvaQ5F0BCZMJt/jH4opciRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}