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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5261b81bb2e40f4682795d63f483fc1e006bcaf0ff2003b31a5fa8450eb7ac4c' 
  AND token = 'lJZIEN8I5CV6kxMh2FbSnAX2wB3SzBM7DtmjUMNLfTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}