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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c647e6eb87702345d55049955f6a5bf37f2a51832476c257ba6edd74724d9dbc' 
  AND token = 'k0hjRqIR37N12bEq0HJ+GD0RtGSmZ2UvSnmdaOr0VUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}