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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10cceba6ead90909582bfc55c1e545da0c996a443be595198b68f4b51f64108a' 
  AND token = '7C/taruS3mxialzOfFVg3HQYWI+OSVtBmo94/irRCg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}