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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '657113c4e9ce0e9f4654e420f56c3457b903b6d72a029e5a7a909f1b37c8388d' 
  AND token = 'SNcg8Wy4UXJxwEXi/eNOU/KEMX614DMTZqW/UJFx4JA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}