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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c2809e65df56f0cf09edab16ad67108c1435b0581e5768f3ad59a99e4cc58a0' 
  AND token = 'p6+xjIGR2jmF91B+I4e2ADtoU4Wx1EErICniMVAYV1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}