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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b200f20d9c396ebc41a25e281cc468c4cb59d694b4a05fe7fa0baca5d1d6b9a6' 
  AND token = 'NBuiC4GvQOsGVWliK3wYinI5Cvj7P2nEd8C7ELGlaR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}