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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39b5badfaded49728ece4b86bb2c97ef37f6324173475373d0d379192da0d266' 
  AND token = 'yvz3cqU7zR0I9p7CKD/e+E/oVoNp4osSHUtALbJGYd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}