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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f999ef45b64772a6b292d0d723c9f4fdf02fdb824d5a912c416ddac222e319' 
  AND token = 'TUlAhMyPUqEyJ3W0W8pxm+CGtft+2sHAUkm+Ab2Spso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}