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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0d8bcd11b287d424a344784255e3e8960c04f051fbc56d1496dd01b704400e7' 
  AND token = 'dXUcyg6aEtQ8EsjAKOFPo5Xnyt4/7ZhMN7ZhvWrmES8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}