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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd85809a778e8cd1377801a37213b5010ba8879d5213d1ebdf6b85a1a79f7ac0e' 
  AND token = 'UZGpMe1BBI55q2JWXQ5mpVGA3eK4d2Ez6PkwgQ/Aeok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}