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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc6dfc5b699958230b8e40fe14962f368d6f8541d3653f3a26bdfe32556a8155' 
  AND token = 'A+0gsNM2UhQoo2EFE/MEdEWCxPacWAF+3NMsMa0Yhfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}